The inaugural PDB50 event was held virtually in May 2021. Click here to watch the full symposium. To access individual presentations, click on the links below.

Speakers

Eddy Arnold

• Rutgers, The State University of New Jersey
• Using HIV-1 reverse transcriptase structures to guide anti-AIDS drug discovery
  Watch Presentation

Helen M. Berman

• Rutgers, The State University of New Jersey
• University of Southern California
• The evolution of the Protein Data Bank as a community resource
  Watch Presentation

Thomas L. Blundell

• University of Cambridge
• A personal history of five decades of structural biology and the PDB: From the X-ray structure of 2-Zinc
  insulin hexamer in 1970 to Cryo-EM structures of DNA-PK from DNA repair in 2020
  Watch Presentation

Alexandre M. J. J. Bonvin

• Utrecht University
• Solving 3D puzzles by integrative modelling using PDB structures
  Watch Presentation

Stephen K. Burley

• Rutgers, The State University of New Jersey
• University of California, San Diego
• Impact of structural biologists and fifty years of Protein Data Bank operations on drug discovery and development
  Watch Presentation

Wah Chiu

• Stanford University
• Cryo-EM of biomolecules at Ångström resolutions
  Watch Presentation

Johann Deisenhofer

• University of Texas Southwestern Medical Center
• 50 years of PDB — from crazy idea to treasure
  Watch Presentation

Juli Feigon

• University of California, Los Angeles
• Structural biology of telomerase
  Watch Presentation

Angela M. Gronenborn

• University of Pittsburgh
• Integrated BioNMR — getting by with a little help from my friends
  Watch Presentation

Jennifer L. Martin

• University of Wollongong
• Science, crystallography, reflections: A journey with the PDB over 35 years
  Watch Presentation

Stephen L. Mayo

• California Institute of Technology
• Antibody small molecule conjugates with computationally designed target binding synergy
  Watch Presentation

Zihe Rao

• ShanghaiTech University
• Tsinghua University
• Structural insight into SARS-CoV-2 replication and transcription complex (RTC)
  Watch Presentation

Hao Wu

• Harvard Medical School
• Boston Children's Hospital
• "Speck"tacular inflammasomes: structures of supramolecular complexes in innate immunity
  Watch Presentation

Poster Presentations

~275 posters were presented during the meeting

Abstracts: Tuesday May 4 (PDF) | Wednesday May 5 (PDF)

wwPDB Posters: The Life and Times of the PDB Format - Looking Towards the Future with mmCIF (PDF)

Trends in macromolecular structure data across 50 years of the PDB (PDF)

Poster Prizes

Best in High School:

Nicholas Mamisashvili

• Shelter Island High School
• Molecular Dynamics Simulation of 6PEY.pdb a Novel Mutation in the Enzyme Methylenetetrahydrofolate Reductase

Best in Undergraduate:

Ijeoma Okoye

• Vassar College
• X-ray and Antioxidant Determination of Butein and 2’,4’-dihydroxy-3,4-dimethoxychalcone to
  Examine their Antimalarial Activity by Binding to Falcipain-2

Best in Graduate:

Daniel Sultanov

• New York University
• Mining for functional ribosomal variants in Saccharomyces cerevisiae

Best in Postdoctoral Scholars:

Seda Kocaman

• National Institute of Environmental Health Sciences
• Different ATP binding states of the essential AAA (ATPases Associated with various Activities)-ATPase
  Rix7 facilitate substrate translocation in ribosome biogenesis

Acknowledgements

PDB50 was organized by members of the wwPDB Foundation:

• Celia Schiffer, University of Massachusetts Medical School
• Helen M. Berman, Rutgers, The State University of New Jersey; RCSB PDB
• Stephen K. Burley, Rutgers, The State University of New Jersey; RCSB PDB
• Jeffrey C. Hoch, University of Connecticut; BMRB
• Gerard J. Kleywegt, European Bioinformatics Institute; PDBe
• Genji Kurisu, Osaka University; PDBj
• John L. Markley, University of Wisconsin–Madison; BMRB
• Sameer Velankar, European Bioinformatics Institute; PDBe
• Christine Zardecki, Rutgers, The State University of New Jersey; RCSB PDB

The organizers thank these sponsors for their generous support of PDB50: