In April 2018, The Office of Research Integrity (ORI) of the U.S. Department of Health and Human Services announced their final Research Misconduct Finding in the case of H.M. Krishna Murthy. It was found that Murthy reported falsified and/or fabricated research in 10 journal publications and 12 corresponding PDB structures. While the ORI was deliberating, 5 Murthy structures in the PDB were obsoleted in accord with wwPDB policies in response to retraction of 4 journal publications (Table 1). In response to a formal request from ORI received on April 13, 2018, the remaining 7 Murthy structures in the PDB were obsoleted, again in accord with wwPDB policies (Table 2).
Typically, authors request that a previously released structure be obsoleted when superseded by a replacement structure resulting from an alternative interpretation of existing data or improved experimental data.
Per wwPDB policy, circumstances occasionally arise under which an obsoleted structure is not superseded by a replacement structure.
In all cases, the entry must contain a statement specifying the reason for obsoleting the structure.
In December 2009, the University of Alabama at Birmingham (UAB) announced that it planned to retract 12 PDB entries and 10 related publications authored by H.M. Krishna Murthy, in his capacity as Principal Investigator and UAB employee. Following wwPDB review of structures at the request of UAB and in accord with wwPDB policy, 5 of the structures were obsoleted following retraction of the related publications by the journals. Following wwPDB review of structures at the request of UAB and in accord with wwPDB policy, the remaining 7 structures were obsoleted following receipt of the ORI request.
Table 1. PDB entries reviewed at the request of UAB and obsoleted following journal retractions.
Table 2. PDB entries reviewed at the request of UAB and obsoleted following receipt of the ORI request.
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