PDB Entry - 2C2S

(Status - Released)

Summary information:

Title: Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-(1-o-carboranylmethyl)-6-methylpyrimidine, A novel boron containing, nonclassical Antifolate

PDB DOI: https://doi.org/10.2210/pdb2c2s/pdb

Primary publication DOI: https://doi.org/10.1021/JM0701977

Entry authors: Leung, A.K.W., Reynolds, R.C., Riordan, J.M., Borhani, D.W.

Initial deposition on: 29 September 2005

Initial release on: 10 April 2007

Latest revision on: 8 May 2019

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (XML)

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