PDB Entry - 2UWD

(Status - Released)

Summary information:

Title: Inhibition of the HSP90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole, isoxazole amide analogs

PDB DOI: https://doi.org/10.2210/pdb2uwd/pdb

Primary publication DOI: https://doi.org/10.1158/1535-7163.MCT-07-0149

Entry authors: Sharp, S.Y., Prodromou, C., Boxall, K., Powers, M.V., Holmes, J.L., Box, G., Matthews, T.P., Cheung, K.M., Kalusa, A., James, K., Hayes, A., Hardcastle, A., Dymock, B., Brough, P.A., Barril, X., Cansfield, J.E., Wright, L.M., Surgenor, A., Foloppe, N., Aherne, W., Pearl, L., Jones, K., McDonald, E., Raynaud, F., Eccles, S., Drysdale, M., Workman, P.

Initial deposition on: 20 March 2007

Initial release on: 24 April 2007

Latest revision on: 13 December 2023

Downloads:

Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (XML)

Validation report (mmCIF)

Validation report (PDF)

Links to more resources for 2UWD at: