PDB Entry - 4BFR

(Status - Released)

Summary information:

Title: Discovery and Optimization of Pyrimidone Indoline Amide PI3Kbeta Inhibitors for the Treatment of Phosphatase and TENsin homologue (PTEN)-Deficient Cancers

PDB DOI: https://doi.org/10.2210/pdb4bfr/pdb

Primary publication DOI: https://doi.org/10.1021/JM401642Q

Entry authors: Certal, V., Carry, J.C., Halley, F., Virone-Oddos, A., Thompson, F., Filoche-Romme, B., El-Ahmad, Y., Karlsson, A., Charrier, V., Delorme, C., Rak, A., Abecassis, P.Y., Amara, C., Vincent, L., Bonnevaux, H., Nicolas, J.P., Mathieu, M., Bertrand, T., Marquette, J.P., Michot, N., Benard, T., Perrin, M.A., Perron, S., Monget, S., Gruss-Leleu, F., Doerflinger, G., Guizani, H., Brollo, M., Delbarre, L., Bertin, L., Richepin, P., Loyau, V., Garcia-Echeverria, C., Lengauer, C., Schio, L.

Initial deposition on: 22 March 2013

Initial release on: 15 January 2014

Latest revision on: 20 December 2023

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Structure coordinates (PDB)

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