PDB Entry - 5CGC

(Status - Released)

Summary information:

Title: Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator 3-chloro-4-fluoro-5-[6-(1H-pyrazol-1-yl)pyrimidin-4-yl]benzonitrile

PDB DOI: https://doi.org/10.2210/pdb5cgc/pdb

Primary publication DOI: https://doi.org/10.1021/acs.jmedchem.5b00892

Entry authors: Christopher, J.A., Aves, S.J., Bennett, K.A., Dore, A.S., Errey, J.C., Jazayeri, A., Marshall, F.H., Okrasa, K., Serrano-Vega, M.J., Tehan, B.G., Wiggin, G.R., Congreve, M.

Initial deposition on: 9 July 2015

Initial release on: 12 August 2015

Latest revision on: 10 January 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (XML)

Validation report (PDF)

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