PDB Entry - 5TLP

(Status - Released)

Summary information:

Title: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-BSC Analog, 3-fluorophenyl (1R,2R,4S)-5-(4-hydroxyphenyl)-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate and 3-methyl-6-phenyl-3H-imidazo[4,5-b]pyridin-2-amine

PDB DOI: https://doi.org/10.2210/pdb5tlp/pdb

Primary publication DOI: https://doi.org/10.1016/j.chembiol.2016.11.014

Entry authors: Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Nowak, J., Kojetin, D.J., Elemento, O., Katzenellenbogen, J.A., Nettles, K.W.

Initial deposition on: 11 October 2016

Initial release on: 18 January 2017

Latest revision on: 6 March 2024

Downloads:

Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (XML)

Links to more resources for 5TLP at: