PDB Entry - 5UG8

(Status - Released)

Summary information:

Title: Crystal structure of the EGFR kinase domain (L858R, T790M, V948R) in complex with a covalent inhibitor N-[(3R,4R)-4-fluoro-1-{6-[(1-methyl-1H-pyrazol-4-yl)amino]-9-(propan-2-yl)-9H-purin-2-yl}pyrrolidin-3-yl]propanamide

PDB DOI: https://doi.org/10.2210/pdb5ug8/pdb

Primary publication DOI: https://doi.org/10.1021/acs.jmedchem.6b01894

Entry authors: Gajiwala, K.S., Ferre, R.A.

Initial deposition on: 7 January 2017

Initial release on: 22 March 2017

Latest revision on: 26 April 2017

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (XML)

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