PDB Entry - 6GIN

(Status - Released)

Summary information:

Title: Crystal structure of the ACVR1 (ALK2) kinase in complex with an Quinazolinone based ALK2 inhibitor with a 4-morpholinophenyl solvent accessible group.

PDB DOI: https://doi.org/10.2210/pdb6gin/pdb

Primary publication DOI: https://doi.org/10.1021/acs.jmedchem.8b00782

Entry authors: Williams, E., Hudson, L., Bezerra, G.A., Kopec, J., Mahajan, P., Kupinska, K., Hoelder, S., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N.

Initial deposition on: 14 May 2018

Initial release on: 23 May 2018

Latest revision on: 17 January 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (XML)

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