PDB Entry - 6JT4

(Status - Released)

Summary information:

Title: Crystal Structure of BACE1 in complex with N-{3-[(4S,6S)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide

PDB DOI: https://doi.org/10.2210/pdb6jt4/pdb

Primary publication DOI: https://doi.org/10.1002/cmdc.201900478

Entry authors: Anan, K., Iso, Y., Oguma, T., Nakahara, K., Suzuki, S., Yamamoto, T., Matsuoka, E., Ito, H., Sakaguchi, G., Ando, S., Morimoto, K., Kanegawa, N., Kido, Y., Kawachi, T., Fukushima, T., Teisman, A., Urmaliya, V., Dhuyvetter, D., Borghys, H., Austin, N., Bergh, A.V.D., Verboven, P., Bischoff, F., Gijsen, H.J.M., Yamano, Y., Kusakabe, K.I.

Initial deposition on: 8 April 2019

Initial release on: 15 January 2020

Latest revision on: 22 November 2023

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (mmCIF)

Validation report (XML)

Validation report (PDF)

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