PDB Entry - 6VFZ

(Status - Released)

Summary information:

Title: Crystal Structure of Human Mitochondrial Isocitrate Dehydrogenase (IDH2) R140Q Mutant Homodimer in Complex with NADPH and AG-881 (Vorasidenib) Inhibitor.

PDB DOI: https://doi.org/10.2210/pdb6vfz/pdb

Primary publication DOI: https://doi.org/10.1021/acsmedchemlett.9b00509

Entry authors: Padyana, A., Jin, L.

Initial deposition on: 7 January 2020

Initial release on: 5 February 2020

Latest revision on: 11 October 2023

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (mmCIF)

Validation report (XML)

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