PDB Entry - 7G2S (pdb_00007g2s)

(Status - Released)

Summary information:

Title: Crystal Structure of rat Autotaxin in complex with 4-[2-oxo-2-[4-[[4-(trifluoromethyl)phenyl]methyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]ethyl]sulfanylbenzenesulfonamide, i.e. SMILES c1(C(F)(F)F)ccc(Cc2c3CN(C(=O)CSc4ccc(S(=O)(=O)N)cc4)CCc3ncn2)cc1 with IC50=3.44948 microM

PDB DOI: https://doi.org/10.2210/pdb7g2s/pdb

Entry authors: Stihle, M., Benz, J., Hunziker, D., Mattei, P., Rudolph, M.G.

Initial deposition on: 5 June 2023

Initial release on: 18 December 2024

Latest revision on: 18 December 2024

Downloads:

Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDB)

Structure coordinates (PDBML)

X-ray diffraction data (PDBx/mmCIF)

Validation report (XML)

Validation report (mmCIF)

Validation report (PDF)

Links to more resources for 7G2S (pdb_00007g2s) at: