PDB Entry - 7G4U (pdb_00007g4u)

(Status - Released)

Summary information:

Title: Crystal Structure of rat Autotaxin in complex with (E)-1-[(3aS,8aR)-2-[(5R)-4,5,6,7-tetrahydro-1H-benzotriazole-5-carbonyl]-1,3,3a,4,5,7,8,8a-octahydropyrrolo[3,4-d]azepin-6-yl]-3-[4-(trifluoromethoxy)phenyl]prop-2-en-1-one, i.e. SMILES C1C[C@@H]2[C@H](CCN1C(=O)/C=C/c1ccc(cc1)OC(F)(F)F)CN(C2)C(=O)[C@@H]1CCC2=C(C1)N=NN2 with IC50=0.0213266 microM

PDB DOI: https://doi.org/10.2210/pdb7g4u/pdb

Entry authors: Stihle, M., Benz, J., Hunziker, D., Mattei, P., Rudolph, M.G.

Initial deposition on: 5 June 2023

Initial release on: 18 December 2024

Latest revision on: 18 December 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDB)

Structure coordinates (PDBML)

X-ray diffraction data (PDBx/mmCIF)

Validation report (XML)

Validation report (mmCIF)

Validation report (PDF)

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