PDB Entry - 7G6O (pdb_00007g6o)

(Status - Released)

Summary information:

Title: Crystal Structure of rat Autotaxin in complex with 6-[(3aR,6aR)-5-[5-cyclopropyl-6-(oxan-4-yloxy)pyridine-3-carbonyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-2-carbonyl]pyridine-3-sulfonamide, i.e. SMILES N1(C[C@@H]2[C@@H](C1)CN(C2)C(=O)c1cc(c(nc1)OC1CCOCC1)C1CC1)C(=O)c1ncc(cc1)S(=O)(=O)N with IC50=0.0360867 microM

PDB DOI: https://doi.org/10.2210/pdb7g6o/pdb

Entry authors: Stihle, M., Benz, J., Hunziker, D., Mattei, P., Rudolph, M.G.

Initial deposition on: 5 June 2023

Initial release on: 18 December 2024

Latest revision on: 18 December 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDB)

Structure coordinates (PDBML)

X-ray diffraction data (PDBx/mmCIF)

Validation report (XML)

Validation report (PDF)

Validation report (mmCIF)

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