PDB Entry - 7RT2

(Status - Released)

Summary information:

Title: Crystal Structure of KRAS G12D with compound 25 (4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)naphthalen-2-ol) bound

PDB DOI: https://doi.org/10.2210/pdb7rt2/pdb

Primary publication DOI: https://doi.org/10.1021/acs.jmedchem.1c01688

Entry authors: Gunn, R.J., Thomas, N.C., Xiaolun, W., Lawson, J.D., Marx, M.A.

Initial deposition on: 12 August 2021

Initial release on: 22 December 2021

Latest revision on: 6 March 2024

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (XML)

Validation report (PDF)

Validation report (mmCIF)

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