PDB Entry - 7RT5

(Status - Released)

Summary information:

Title: Crystal structure of KRAS G12D with compound 36 (4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-7-(8-ethynyl-7-fluoronaphthalen-1-yl)-8-fluoro-2-{[(4s,7as)-tetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidine) bound

PDB DOI: https://doi.org/10.2210/pdb7rt5/pdb

Primary publication DOI: https://doi.org/10.1021/acs.jmedchem.1c01688

Entry authors: Gunn, R.J., Thomas, N.C., Xiaolun, W., Lawson, J.D., Marx, M.A.

Initial deposition on: 12 August 2021

Initial release on: 22 December 2021

Latest revision on: 18 October 2023

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

Structure coordinates (PDB)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (XML)

Validation report (mmCIF)

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