PDB Entry - 8EIO (pdb_00008eio)

(Status - Released)

Summary information:

Title: The complex of phosphorylated human delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) with elexacaftor (VX-445), lumacaftor (VX-809) and ATP/Mg

PDB DOI: https://doi.org/10.2210/pdb8eio/pdb

Primary publication DOI: https://doi.org/10.1126/science.ade2216

Entry authors: Fiedorczuk, K., Chen, J.

Initial deposition on: 15 September 2022

Initial release on: 19 October 2022

Latest revision on: 21 May 2025

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDB)

Structure coordinates (PDBML)

Validation report (XML)

Validation report (PDF)

Validation report (mmCIF)

EM map volume (CCP4)

Links to more resources for 8EIO (pdb_00008eio) at: