PDB Entry - 9EC2 (pdb_00009ec2)

(Status - Released)

Summary information:

Title: Crystal structure of SAMHD1 dimer bound to an inhibitor obtained from high-throughput chemical tethering to the guanine antiviral acyclovir

PDB DOI: https://doi.org/10.2210/pdb9ec2/pdb

Primary publication DOI: https://doi.org/10.1021/acs.biochem.4c00854

Entry authors: Egleston, M., Dong, L., Howlader, A.H., Bhat, S., Orris, B., Lopez-Rovira, L.M., Bianchet, M.A., Greenberg, M.M., Stivers, J.T.

Initial deposition on: 13 November 2024

Initial release on: 12 March 2025

Latest revision on: 19 March 2025

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

X-ray diffraction data (PDBx/mmCIF)

Validation report (PDF)

Validation report (mmCIF)

Validation report (XML)

Links to more resources for 9EC2 (pdb_00009ec2) at: