PDB Entry - 9NZM (pdb_00009nzm)

(Status - Released)

Summary information:

Title: Crystal Structure of Kirsten Rat Sarcoma G12C Complexed with GMPPNP and Covalently Bound to an Adduct of {(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]-1-[(2Z)-2-fluoro-3-(pyridin-2-yl)prop-2-enoyl]piperazin-2-yl}acetonitrile

PDB DOI: https://doi.org/10.2210/pdb9nzm/pdb

Entry authors: Sheriff, S., Pokross, M., Witmer, M.

Initial deposition on: 1 April 2025

Initial release on: 5 November 2025

Latest revision on: 5 November 2025

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Structure coordinates (PDBx/mmCIF)

Structure coordinates (PDBML)

X-ray diffraction data (PDBx/mmCIF)

Validation report (mmCIF)

Validation report (XML)

Validation report (PDF)

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